

Implementation of MA QC has added value for our laboratory setting.

For the other parameters, we identified MA utilization beyond real-time monitoring. For three parameters a direct MA alarm work-up method was set up, including newly developed built-in features in the LIS. For the six remaining parameters, MA QC showed added value to IQC and was therefore implemented in the LIS. Three out of nine parameters (Hb, ESR, and sodium) were excluded from MA QC implementation due to high variation and technical issues in the LIS. After this, MA QC settings were incorporated in our LIS for further evaluation and implementation in routine care. Using data extractions from the laboratory information system (LIS General Laboratory Information Management System), evaluation of usefulness and optimization of MA QC settings was performed using bias detection curves. Nine parameters (serum sodium, calcium, bicarbonate and free thyroxine, hemoglobin, mean corpuscular volume, mean corpuscular hemoglobin concentration, reticulocyte count and erythrocyte sedimentation rate ) were chosen for initial consideration.


We describe the evaluation process and provide practical tools to aid MA QC implementation. We implemented MA QC for multiple routine hematology and chemistry parameters. Advantages compared to conventional periodic internal quality control (IQC) include absence of commutability problems and continuous monitoring of performance. Moving average quality control (MA QC) is a patient-based real-time quality control system.
